Gut Reaction, part of the NIHR BioResource, is a unique, secure data resource designed to facilitate academic and industry research in Inflammatory Bowel Disease (IBD). Gut Reaction brings together patient data from the IBD BioResource cohort with a patient’s clinical records and makes it available to researchers on a much broader scale than ever before. Patient trust and privacy is critical to Gut Reaction’s success. Privitar allows Gut Reaction to easily, readily, and repeatedly de-identify data so they can maintain privacy and still allow access for research.